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Choroid Plexus Papilloma (CPP): Overview
- Together with Teratoma, PNET, and High Grade Glioma is one of the most common frequent brain tumors before age of 2 years.
- It comprises less than 1% of brain tumors.
- These are typically located in the lateral ventricle (50%), or in the fourth ventricle (40% and more commonly in adults). Ten percent of these tumors are in the third ventricle, and rarely in the cerebellopontine angle (CPA). They are rarely bilateral (4%).
- They are typically well circumscribed, vascular, and contrast enhancing.
- Patients typically present with hydrocephalus as a result of increased cerebrospinal fluid (CSF) production, or due to blockage of CSF flow from direct obstruction of hemorrhage.
- Surgical resection usually has a good outcome with rare recurrences.
- There are rare malignant transformations.
- As with intraventricular meningiomas, they are more frequently on the left intraventricular space.
- This tumor needs to be differentiated from choroid plexus carcinoma (CPC) which has 15% incidence of CPPs. CPCs usually invade the parenchyma of brain and seed the CSF. Treatment of CPC is with surgery and radiation with or without chemotherapy with poor prognosis.
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Last Updated on Sunday, 08 January 2012 20:24 |
